Philippe E Van den Steen Selected Research

Matrix Metalloproteinase 9 (Gelatinase B)

11/2019	Matrix metalloproteinase-9 induces a pro-angiogenic profile in chronic lymphocytic leukemia cells.
1/2018	A catalytically inactive gelatinase B/MMP-9 mutant impairs homing of chronic lymphocytic leukemia cells by altering migration regulatory pathways.
1/2014	Inhibition of neutrophil collagenase/MMP-8 and gelatinase B/MMP-9 and protection against endotoxin shock.
5/2013	Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): the next decade.
1/2013	Natural haemozoin induces expression and release of human monocyte tissue inhibitor of metalloproteinase-1.
8/2012	Definition of peptide inhibitors from a synthetic peptide library by targeting gelatinase B/matrix metalloproteinase-9 (MMP-9) and TNF-α converting enzyme (TACE/ADAM-17).
8/2011	Natural haemozoin modulates matrix metalloproteinases and induces morphological changes in human microvascular endothelium.
5/2011	Deficiency of gelatinase B/MMP-9 aggravates lpr-induced lymphoproliferation and lupus-like systemic autoimmune disease.
2/2010	Matrix metalloproteinase-9 promotes chronic lymphocytic leukemia b cell survival through its hemopexin domain.
12/2008	Increased gelatinase B/matrix metalloproteinase 9 (MMP-9) activity in a murine model of acute coxsackievirus B4-induced pancreatitis.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Philippe E Van den Steen Research Topics

Disease

21	Malaria 01/2022 - 05/2010
20	Inflammation (Inflammations) 10/2018 - 03/2002
10	Neoplasms (Cancer) 03/2014 - 12/2006
8	Cerebral Malaria 01/2020 - 09/2006
8	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2019 - 05/2010
7	Infections 01/2020 - 09/2006
7	Autoimmune Diseases (Autoimmune Disease) 05/2013 - 01/2003
5	Septic Shock (Toxic Shock Syndrome) 01/2014 - 08/2005
4	Shock 01/2014 - 09/2006
4	Multiple Sclerosis 04/2006 - 01/2003
3	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 11/2019 - 02/2010
3	Edema (Dropsy) 01/2019 - 05/2013
3	Pancreatitis 12/2008 - 01/2003
3	Rheumatoid Arthritis 04/2006 - 03/2002
2	Necrosis 01/2018 - 09/2008
2	Pathologic Processes 06/2015 - 12/2002
2	Rupture 01/2014 - 05/2012
2	Sepsis (Septicemia) 05/2013 - 08/2005
2	Bacterial Meningitis 05/2013 - 08/2005
2	Vascular Diseases (Vascular Disease) 02/2008 - 06/2007
2	Breast Neoplasms (Breast Cancer) 12/2006 - 01/2005
1	Hyperlactatemia 01/2021
1	Anemia 01/2021
1	Lactic Acidosis 01/2021
1	Kidney Diseases (Kidney Disease) 01/2021
1	Parasitemia 10/2018
1	Hypoglycemia (Reactive Hypoglycemia) 10/2018
1	Pulmonary Edema 01/2017
1	Chronic Disease (Chronic Diseases) 05/2013
1	Pneumonia (Pneumonitis) 05/2013
1	Fibrosis (Cirrhosis) 12/2012
1	Cytokine Release Syndrome 08/2012
1	Acute Lung Injury 08/2012
1	Brain Diseases (Brain Disorder) 05/2012
1	Trypanosomiasis 03/2012
1	Parasitic Diseases (Parasitic Disease) 03/2012
1	Leishmaniasis 03/2012
1	Toxoplasmosis 03/2012
1	Neuroinflammatory Diseases 08/2011
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 05/2011
1	Autoimmune Lymphoproliferative Syndrome 05/2011
1	Splenomegaly 05/2011

Drug/Important Bio-Agent (IBA)

27	Matrix Metalloproteinase 9 (Gelatinase B)IBA 11/2019 - 03/2002
17	Matrix Metalloproteinases (MMPs)IBA 01/2018 - 03/2002
7	CytokinesIBA 01/2020 - 04/2006
7	EnzymesIBA 10/2018 - 03/2002
7	hemozoinIBA 01/2018 - 08/2011
7	Matrix Metalloproteinase InhibitorsIBA 03/2014 - 06/2003
7	Peptide Hydrolases (Proteases)FDA Link 12/2012 - 03/2002
5	Metalloproteases (Metalloproteinases)IBA 01/2020 - 09/2006
5	Proteins (Proteins, Gene)FDA Link 01/2019 - 12/2002
3	GlucocorticoidsIBA 11/2019 - 01/2016
3	Dexamethasone (Maxidex)FDA LinkGeneric 11/2019 - 05/2010
3	Insulin (Novolin)FDA Link 10/2018 - 01/2003
3	LipidsIBA 01/2018 - 08/2011
3	ChemokinesIBA 06/2015 - 04/2008
3	Matrix Metalloproteinase 8 (Neutrophil Collagenase)IBA 01/2014 - 08/2005
3	Biological ProductsIBA 05/2013 - 07/2009
2	Antimalarials (Antimalarial Agents)IBA 01/2020 - 03/2018
2	von Willebrand FactorIBA 01/2020 - 01/2019
2	Hormones (Hormone)IBA 10/2018 - 01/2016
2	Complement System Proteins (Complement)IBA 01/2014 - 09/2006
2	AntibodiesIBA 01/2014 - 01/2003
2	ZincIBA 12/2012 - 10/2007
2	HemopexinIBA 02/2010 - 04/2007
2	Crystallins (Crystallin)IBA 01/2005 - 08/2003
2	AutoantigensIBA 08/2003 - 01/2003
2	EpitopesIBA 01/2003 - 03/2002
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2021
1	ThrombospondinsIBA 01/2020
1	DisintegrinsIBA 01/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2019
1	Freund's AdjuvantIBA 01/2019
1	Liver GlycogenIBA 10/2018
1	Glucose (Dextrose)FDA LinkGeneric 10/2018
1	AntioxidantsIBA 01/2018
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017
1	Virulence Factors (Pathogenicity Factors)IBA 03/2016
1	Hemoglobins (Hemoglobin)IBA 06/2015
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 06/2015
1	Pharmaceutical PreparationsIBA 06/2015
1	Surface-Active Agents (Surfactants)IBA 01/2015
1	Angiogenic ProteinsIBA 03/2014
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2014
1	InflammasomesIBA 01/2014
1	Peptides (Polypeptides)IBA 01/2014
1	Tissue Inhibitor of Metalloproteinase-1IBA 01/2013
1	p38 Mitogen-Activated Protein KinasesIBA 01/2013
1	Tiopronin (Thiola)FDA Link 12/2012
1	astacinIBA 12/2012
1	TetracyclinesIBA 03/2012
1	pro-matrix metalloproteinase 9IBA 08/2011
1	AutoantibodiesIBA 05/2011

Therapy/Procedure

4	Therapeutics 05/2012 - 06/2003
2	Immunotherapy 01/2014 - 06/2003
1	Adrenalectomy 10/2018
1	Intraperitoneal Injections 01/2014
1	Injections 01/2014